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Ph.D.

Study: Traffic Air Pollution Increases Pregnant Women’s Blood Pressure

A new report from the National Toxicology Program suggests that traffic-related air pollution increases a pregnant woman’s risk for dangerous increases in blood pressure, known as hypertension.

NTP scientists evaluated published research on the link between traffic-related air pollution, or TRAP, and hypertensive disorders broken down by pollutant measurements of TRAP, such as particulate matter (PM2.5). PM is the term for a mixture of solid particles and liquid droplets found in the air, and PM2.5 refers to fine inhalable particles, with diameters that are generally 2.5 micrometers or smaller. The average human hair is about 70 micrometers in diameter, about 30 times larger than the largest fine particle.

“What we found when we reviewed the literature is that exposure to PM2.5 from traffic emissions was associated with development of hypertensive disorders in pregnant women,” said Brandy Beverly, Ph.D., lead scientist and researcher at the National Institute of Environmental Health Sciences, part of the National Institutes of Health. “When these women are exposed to PM2.5 during their entire pregnancy, the likelihood of developing preeclampsia increases by about 50%.”

Other components of TRAP that NTP evaluated included nitrogen oxides, carbon monoxide, black carbon, and elemental carbon, along with parameters like traffic density and mothers’ proximity to main roads.

For example, the literature suggests that women who live within a quarter of a mile of a major roadway or in high traffic density regions may be at an increased risk for developing hypertensive disorders of pregnancy.

TRAP comes from the combustion of fossil fuels by motor vehicles. These vehicle emissions are mixtures of gases and particles that are easily inhaled and have adverse health effects. TRAP is known to be a major risk factor for cardiovascular disease, including hypertension.

Hypertensive disorders of pregnancy complicate more than 10% of pregnancies worldwide and are a leading cause of maternal and fetal illness and death. According to the American College of Obstetrics and Gynecology, mothers with hypertension during pregnancy are more likely to have a pre-term delivery. Their infants are at greater risk for low birthweight and a range of long-term health problems associated with pre-mature birth.

“Hypertensive disorders of pregnancy refer to a range of clinical conditions, all of which include high blood pressure during pregnancy,” said Beverly. “The disorders are classified into four distinct types, based on differences in the timing and onset of the symptoms.”

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Tackle Procrastination in Kids By Understanding What Motivates Them to Get Things Done

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 Mary Lamia, Ph.D.*

Melissa always gets things done ahead of time and enjoys the relief she feels as she crosses tasks off her list. This was the case, she recalls, as far back as grammar school where she didn’t feel good about going out to play until her homework was finished. In contrast, her older son, Tyler, seems to have a very different way of doing things. Similar to how his dad recalls how he got things done in school, Tyler plays first and does homework later, often finishing minutes before his strict bedtime. Much to Melissa’s displeasure, Tyler uses their short commute to school as time to study for various tests. She gave up lecturing him on time management since, as Tyler’s dad constantly reminds her, Tyler’s grades are excellent. Melissa can easily identify with the way her younger son, Anthony, gets things done—he has an urgency to do things right away, whether it is his homework or packing for a trip. But Anthony’s way of doing things leads to occasional conflict with his dad, such as the time he insisted on finishing a project before going on an outing.

Motivational styles generally develop at a young age, and many people can link their particular style to memories of completing school assignments or everyday tasks. Where some people put things off until a deadline looms, others seem compelled to complete tasks immediately. Does procrastination interfere with success? Definitely not. Those who wait are just as likely to be successful as people who complete tasks ahead of time. The ultimate goals to keep in mind have to do with consistently meeting deadlines and using one’s best efforts.

The different timing of procrastinators and non-procrastinators to complete tasks has to do with when their emotions are activated and what activates them. Procrastinators who consistently complete tasks on time—even if it’s at the last moment—are motivated by emotions that are activated when a deadline is imminent. They are deadline driven. In contrast to procrastinators, task-driven people faced with uncompleted tasks are compelled to take action right away. Motivated by their emotions to complete a task ahead of schedule and put it behind them, those who are successful attend to the quality of their work prior to scratching the task off their list.

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Early childhood response patterns to emotion—such as when emotion was activated that motivated you to complete your homework or clean your room—continue to influence how you tend to get things done throughout your life. You might assume you did these things just because you were supposed to do them. Although you may not have been aware of feeling a particular emotion but instead only thoughts such as, “I should do my homework,” I can assure you that emotion was present that motivated you to do it or not. These early life experiences, at some point, solidify into characteristic emotional responses to tasks and lead to a particular style of getting things done.

Both children and the adults in their lives can benefit from understanding the source of what motivates them. Mistakenly, many parents and teachers believe only positive emotions motivate children in a healthy way. Yet how many children have a motivational system that will trigger the emotion of excitement, for example, in response to several pages of math problems or taking out the garbage? Although children can be motivated by anticipating they will feel positive emotions that result in pride, often what motivates a child to get something done also has to do with their response to negative emotions, such as the avoidance of shame or guilt, or relief from distress (often experienced as a fear of failure or a fear of forgetting).

Just because we experience a negative emotion about a task to complete does not mean we should avoid getting something done or be punished for what is felt. Moreover, many children are confused when they do not feel any positive emotion about a task that is before them, as though that’s always how they should always feel. Instead, caregivers who can be playful with their awareness of how the human motivational system works can activate interest or excitement about the relief that will be felt in completing a dreaded task, along with pride in the outcome.

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*Author of What Motivates Getting Things Done: Procrastination, Emotions, and Success (Rowman and Littlefield). Website: http://www.marylamia.com 
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Study: Accupuncture Alone is Not a Cure for Infertility

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Acupuncture has long been suggested as a means for cure or respond to infertility, in particular PCOSPolycystic Ovarian Syndrome, but a new study suggests that it does not improve chances of having a baby.

In a collaboration between the researchers in China, the United States and Europe, researchers found that acupuncture is ineffective in improving live birth rate in women with, or PCOS, contrary to prevailing wisdom and common practice.

PCOS is the most common form of infertility connected to a lack of ovulation, and affects up to 10 percent of women of reproductive age. Symptoms of PCOS, in addition to the absence of ovulation, can include irregular menstruation; high levels of androgens, a type of hormone; and ovarian cysts.

In China and increasingly around the world, acupuncture, a fundamental part of Chinese medicine, is thought to induce ovulation and in turn improve live birth rate—but no substantive research has yet proved its effectiveness.

The first-line treatment to induce ovulation in women with PCOS is clomiphene. Commonly known by its brand name Clomid, it is a safe and inexpensive medicine that appears on the World Health Organization’s Model List of Essential Medicines.

However, because the drug has a high failure rate, 23.4 percent, researchers are seeking a secondary treatment to modify and improve its performance.

But acupuncture is not an effective option for co-treatment with clomiphene or alone, the study finds.

This is a landmark randomized clinical trial conducted to evaluate Chinese and Western medicine in infertility treatment according to the international standards and under formal advisory of international experts,” said a lead researcher Heping Zhang, Ph.D., Susan Dwight Bliss Professor of Biostatistics at Yale School of Public Health.

In the multicenter trial, 1,000 women in China diagnosed with PCOS were administered acupuncture either in combination with clomiphene or with a placebo. The results showed that while the live birth rate was significantly higher in women who received clomiphene compared to those who received the placebo (28.7 percent versus 15.4 percent), there was little difference in the birth rate between women who received acupuncture as an active agent, or as a control (21.8 percent versus 22.4 percent).

There was also no interaction between clomiphene and acupuncture that led to a higher birth rate.

Read more about the study, published in the journal JAMA here

 

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